DNA cleavage is a research area within molecular biology and genetics that focuses on the process of breaking the bonds that hold together the double helix structure of DNA. This can be done either through enzymatic processes, such as the action of nucleases, or through non-enzymatic processes, such as exposure to certain chemicals or radiation. DNA cleavage plays a crucial role in various biological processes, including DNA replication, repair, and recombination. Studying DNA cleavage can provide insights into the mechanisms underlying these processes, as well as potential applications in areas such as gene editing and cancer therapy.